ROLE SUMMARY

With outstanding presentation and influencing skills CECs will provide compelling value propositions, using both clinical and health economic and population modelling data for investing in Pfizer’s medicines. Working with colleagues, CECs will deliver compelling system value messaging to both payers and clinicians within Integrated Care Systems in England and relevant integrated care bodies in the devolved nations, patient access and guidance for our breakthrough medicines in appropriate patients.

ROLE RESPONSIBILITIES

• Demonstrate internally and externally exceptional policy, environmental, clinical and health outcomes knowledge, to identify and accelerate opportunities to drive growth and deliver system value to the NHS and patients.
• Optimise patient access and growth for our prioritised brands by demonstrating the value of our medicines to Health and Care Systems, through clinical and cost effectiveness data modelling to local populations.
• Collaborate with the Brand Marketing, Sales colleagues, Health and Value, other BUs and Alliances to develop formats for messaging and messages that share the value of our medicines in a Clinical and Payor customer context • Provide insights to inform the development of value propositions based on clinical and health economics expertise, tailored to local need.
• Working with local teams deliver population health system value messaging and modelled outcomes to prioritised customers within ICS at system, place and at all key NHS levels and devolved nations equivalents in order to achieve ICS and priority place-based account plan objectives and sales targets.
• Proactively develop & manage key customer relationships to facilitate the implementation of effective programs and solutions which meet a shared agenda and maximise appropriate use of our medicines within guidelines and pathways.
• Incorporate CEC Digital ways of working to enhance customer experience through use of multi-channel activities i.e. virtual calls, Representative triggered emails (RTEs), e-permissions
• Support all commercial colleagues on the development, implementation, and review of strategic Regional and National Business Plan, through analysis, insights and other expertise.
• Collaborate with local team and other One Pfizer colleagues to share information, motivate, and support team members to ensure impactful, valuable customer interactions, including upskilling, and continuous professional development.
• Ensure relevant administrative systems are maintained and updated to ensure accurate recording of personal activity, progress on LHE plans and customer information and interactions.
• Ensure full adherence to the ABPI Code of Practice and all Pfizer standards, policies and compliance procedures.
• Is sought out by colleagues as a subject matter/role expert for support and guidance as a result of their sustained high level of performance and expertise.
• Supports colleague and peer development as a coach/mentor.
• Demonstrates additional proactive Leadership at a Regional/National level (projects/initiatives/meetings) to impact National performance.
• With a solution focused growth mindset, consistently seeks new opportunities to drive continuous improvement of internal processes and external customer engagement.
• Works cross functionally within BU and across One Pfizer to align and share best practice to deliver on our purpose.
• Understand Health economic and population modelling data.
• Critical Appraisal skills
• Relevant experience.
• Must have gained the ABPI Medical Representative’s Exam (or equivalent) within first two years of employment as a representative.
• Representatives new to the pharmaceutical industry, must take an appropriate exam within their first year of employment as a representative.
• Fully conversant with requirements of ABPI Code of Practice
• Where access to customer groups have certain entry requirements e.g. credentialing, colleague would be required to comply with these as necessary to fulfil their role.
• Promote ongoing learning agility and Continuous Professional Development for self and others, demonstrating a growth mindset.
• Role model Pfizer values and behaviors to ensure our culture is diverse and inclusive.
• The role and customer facing activity will be a mix of face to face and remote working based on customer preference.
• Clinical/Payer/health economics background
• Experience in presenting clinical/health economic data.
• Results driven.
• Resilience
• Experience with detailing technology/Information technology and software packages.
• Project management and delivery

Non-promotional responsibilities

When appropriate, work in a non-promotional capacity with Healthcare Organisations to provide support for, or to develop and deliver solutions that benefit the NHS and/or enhance patient care. Maintain and apply knowledge of the APBI Code and Pfizer policies in relation to Collaborative Working and provision of Grants and Donations, ensuring that clear separation of these activities from promotional responsibilities is maintained at all times.

The Access Engagement (AE) Director will be responsible for developing short-, medium- and long-term external stakeholder engagement strategy and tactics that position Pfizer as a respected leader in the market access (MAx) space and which enhances opportunities for external collaboration that support optimal access and adoption of Pfizer’s medicines and vaccines for the benefit of patients. Crucially, the AE Director will be expected to act independently, using their foresight and extensive current knowledge of the MAx and stakeholder landscape, to prepare recommendations that shape Pfizer’s future approach to stakeholder strategy and engagement. The AE Director will be a recognised expert in MAx negotiations and will have extensive stakeholder engagement experience at a national, senior NHS level. They will help foster motivation across A&V and the broader UK business to support the evolution of an industry leading stakeholder strategy and plan. The main geographic focus for the role will be England. The role responsibilities are anticipated to be distributed approximately 60% BU asset work and 40% external engagement strategy and planning. This engagement strategy and planning element may include a combination of the following responsibilities (which will evolve as the external environment and future business priorities evolve):

Indicative additional responsibilities of the AE Director (included in role responsibilities)

• Own and maintain the national MAx stakeholder strategy and plan (Stakeholder 360) and ensure One Pfizer execution with excellence
• Accountable for the evolution of the national MAx stakeholder strategy and plan based on industry leading up to date knowledge of the evolving stakeholder landscape
• Responsible for ensuring the national MAx stakeholder strategy is aligned and translated into the local NHS strategy and plan (both internally and externally)
• Identify training needs and lead the development and provision of skills training for A&V and broader Pfizer teams in relation to national MAx engagements and translation of guidance into the local NHS
• Be the primary point of contact for NHSE / DHSC medicines pricing, policy and MAx negotiations
• Lead and / or support the highest priority ‘invest to win’ negotiations with NHSE / DHSC
• Accountable for regular updates and recommendations on stakeholder strategy and engagement to the UKMF and A&V LT - be the national MAx expert, single point of contact for Pfizer UK
• Accountable for ensuring an effective stakeholder strategy is developed and aligned across A&V Teams (A&A, HTA, OE) to achieve directorate priorities

GENERAL ROLE SUMMARY:

The Director (A&A) will be responsible for leading the development and execution of MAx strategies for priority pipeline assets across one or more of Pfizer’s business units to ensure timely, sustainable access to Pfizer’s medicines and vaccines for patients in the UK. They will focus primarily on pipeline assets and launch readiness; and will assume the role of lead point of contact for BUs and other platform functions for MAx related activities across pipeline (and some inline / launch) assets.

The Director will lead MAx related deliverables in line with the A&A role critical success factors (CSFs):

• Early Engagement – engage with internal and external stakeholders prior to Phase 3 of clinical development (pre-DP3) to develop a MAx strategy conducive to optimal reimbursement and adoption for UK patients.
• Early Access - lead evaluation of optimal MAx routes, e.g. ILAP, IMF, CDF for pipeline (and some inline) assets. This requires excellent leadership and project management skills to coalesce the UK and global XFT, e.g. A&V, Medical, Commercial, Regulatory, CCT, PPA, PHI.
• Effective Partnerships - build relationships and co-create MAx solutions with external stakeholders, in particular NHSE MVA / emerging similar structures across NHSE / DHSC and equivalent stakeholders in UK devolved nations.

The Director will be the single point of contact for UK BUs and platform functions with regards to MAx and price related topics. This includes being accountable for the approval of price change requests (PCRs) for all of Pfizer’s medicines and vaccines within a BU.

The Director will deliver innovative MAx solutions; they will be able to operate independently while taking considered risks; and they will be solution orientated with an ability to synthesise aligned MAx solutions autonomously.

ROLE RESPONSIBILITIES:

Market Access & Pricing Strategy:

• Lead early pricing and access assessments for pipeline assets (using MAx strategy and/or light touch assessment templates) and ensure that UK needs are represented within global clinical and access strategies

• Lead communication and alignment across global and UK cross-functional teams to deliver a

coherent launch readiness strategy across pricing & reimbursement, access (national & subnational),

external engagement (e.g. NHSE), health technology assessment (HTA), real-world

evidence (RWE) gap analyses etc.

• Lead UK pricing strategy and develop best practices for price optimisation (including tender

excellence where relevant) in Pfizer UK

• Work closely with Global MAx colleagues to develop the value proposition and

negotiation strategy for launch assets, consistent with TLAN principles

• Become the BU A&V strategic lead and provide clear perspectives on priorities and MAx

strategy across the portfolio within a given BU

Competitor & Environmental Dynamics:

• Forecast and address challenges arising in the dynamic UK access environment, anticipate key trends, analyse organisational implications and translate into compelling strategic recommendations that are implemented by the BU and Directorate

• Provide insights and evidence to support national negotiations (e.g. VPAS) and influence/comment on other NHS / MAx policies and consultations that impact the UK access environment

• Compliantly monitor the competitive pricing and access landscape and develop proactive and reactive tactics to manage risks/threats and ensure optimal access and uptake

• Monitor global and UK specific regulatory and access dates, and clinical development programmes for pipeline assets, and lead UK horizon scanning updates, e.g. UK Pharmascan, NIHRIO

Culture & Thought-Leadership:

• Collaborate closely with colleagues across the A&A Team to ensure a one-Pfizer

mindset and perspective in all strategies and customer engagement and help position Pfizer as

market access thought-leaders

• Partner with key stakeholders, academia and relevant institutions (e.g. NHSE, AHSNs, ICSs), in

collaboration with other A&V functions, to build capability and lead the industry in value-based

reimbursement models.

• Work with H&V colleagues to identify new opportunities for value creation based on an

understanding of Health Care systems and the potential benefits of Pfizer medicines.

Join Takeda, a leading global biopharmaceutical company, as a Digital Marketing Apprentice. Gain hands-on experience with digital campaigns, develop new marketing materials, and support the tactical implementation of the brand strategy. Join an innovative team and support the marketing of life-transforming treatments.

Most of your apprenticeship is spent working. You’ll learn on the job by getting hands-on experience.

What you’ll do at work

• Join one of our brand teams working with world class marketeers assisting in the cross functional tactical implementation of the brand strategy engaging with our stakeholders and support patients with our life-transforming treatments
• Be part of and lead key omnichannel marketing campaigns including development of materials (emails, videos, leaflets etc.)
• Support with the logistics and approval process for sales force materials: meeting invitation, slides etc.
• Manage the internal approval process and withdrawals via Promomats (the materials approval database system)
• Assist the brand team with the logistics of internal and external meetings, liaise with our key customers and engage with outside agencies

Based in our UK Head Offices in Central London, Paddington to be exact, with some flexibility around remote work, this role is based within our Marketing function, aligned to our Rare Diseases or Internal Medicine & Vaccines teams.

Where you’ll work

1 KINGDOM STREET
PADDINGTON
LONDON
W2 6BD

Training

Apprenticeships include time away from working for specialist training. You’ll study to gain professional knowledge and skills.

College or training organisation

LONDON SOUTH BANK UNIVERSITY

Your training course

Digital marketer (integrated degree) (level 6)

Equal to degree

Your training plan

• You will study towards obtaining a Bachelor of Science degree in Digital Marketing
• Training will take place at London South Bank University on one day per week

After this apprenticeship

This apprenticeship will equip you with the skills to pursue a variety of careers within the pharmaceutical industry, including marketing roles or the Takeda Graduate Leadership Development Programme.

To provide medical & scientific support to healthcare professionals and professional bodies through scientific communications and support for clinical research to facilitate a medical and scientific bridge between Pfizer and the healthcare community. To provide specialist medical, scientific and Code compliance advice to the nominated internal team(s) to support the appropriate use of Pfizer medicines and successful implementation of Pfizer’s initiatives and programs.

Partnerships

• Activities to build and develop enduring external relationships facilitating a medical and scientific bridge between Pfizer and the healthcare community

Data generation and publication and support for clinical development

• Deliver the medical plan in relation to medical projects, investigator sponsored research (ISR), clinical trials, non- interventional studies, database studies and registries. Shape development program through insights from academic and clinical community and patients. Generate and publish real world data

Data communication and customer insight

• Communicate the value of our medicines through high-quality, accurate, balanced and impactful information. Leverage customer intelligence and insights to shape brand strategy
• Cross functional medical and scientific support
• Support for other departments including Regulatory Affairs, Drug Safety, Medical Information, Health and Value and Corporate Affairs, Customer Operations, Medical Quality and Compliance, Worldwide Research and Development and Clinical Operations

Organizational Relationships: Reports to Medical Therapy Area Lead

Resources Managed: Project budget within medical plan

Primary Duties:

Partnerships

• To provide specialist medical and scientific advice to the nominated internal teams to support the appropriate use of Pfizer medicines and successful implementation of Pfizer’s initiatives and programs.
• To provide medical & scientific support to healthcare professionals and professional bodies through scientific communications and support for clinical research to facilitate a medical and scientific bridge between Pfizer and the healthcare community.
• To liaise with healthcare professionals to effectively communicate and manage drug safety issues
• To build and develop enduring peer-to-peer relationships with leading healthcare professionals and specialists, including non-traditional customers and key decision makers.
• To understand customer insights around current standard of care and to support their knowledge of the value of our medicines to the NHS and patients

Data generation and publication

• To acquire and maintain in-depth scientific knowledge of Pfizer medicines within nominated therapy area(s) (including those in development) as well as of key competitors.
• To deliver the medical plan in relation to medical projects, Investigator Sponsored Research (ISR) and support for Pfizer sponsored clinical research
• To deliver other key medical and scientific activities within the medical plan, eg generation of real world evidence, non-interventional studies, database studies and registries (in collaboration with OREBM colleagues) and ensure timely publication of data

Support for clinical development

• To provide medical/scientific input into protocol feasibility assessments for clinical trial proposals.
• To identify appropriate investigators / sites for Pfizer-sponsored clinical trials.
• To work together with clinical research colleagues and in collaboration with above-country and global BU colleagues to drive the timely completion of Pfizer-sponsored clinical trials
• To provide input into the regional and global clinical teams to ensure design and selection of trials relevant to UK needs, leveraging customer and patient insights
• To support the effective implementation of approved compassionate use and named patient supply programs to ensure appropriate access to Pfizer medicines in response to HCP requests

Data communication and customer insights

• To provide high-quality, accurate, balanced and specific information to customers in response to unsolicited requests for information.
• To provide scientific insight and support to field- and head office based commercial colleagues.
• To work with the cross functional team in-country and above-country to develop impactful and compliant promotional and non-promotional materials of value to customers
• To review (and certify where applicable) promotional and non-promotional materials and activities within scope of the ABPI Code of Practice.
• To ensure customer intelligence is brought into the organisation to generate customer insights, shape future strategy and leverage business opportunities.
• To manage local advisory boards to gain customer insights
• If media-trained, to present the scientific perspective on selected topics during media-briefings

Cross functional medical and scientific support

• Support OREBM in providing medical support for HTA dossiers and regional/local formularies
• Support Regulatory Affairs in responding to questions from regulatory agencies and implementing changes to product SPC, PIL and PI. Provide support for clinical overviews, core datasheet revisions, licence variations, batch specific variations and implementation of Risk Management Plans
• Provide support to Medical Information to facilitate the maintenance of an accurate, relevant and high quality database which would enable them to respond effectively to customer enquiries.
• Provide scientific input to other departments (e.g. Government Affairs, Stakeholder Strategy, Communications, Customer Operations, Medical Quality and Compliance, Pfizer Research and Development groups) on a project-by-project basis
• To provide specialist ABPI Code compliance support to brand/therapy area teams and other departments on customer engagement & partnership activities (e.g. Digital Programs, Joint Working, Medical & Educational Goods & Services, Advisory Boards)
• To develop and maintain ongoing cross-functional working relationships with Pfizer colleagues within the in-country, regional and global BU organisations

When you take on one of our undergraduate placements, you become part of a team that’s working to make the breakthroughs that change patients’ lives, all over the world. You join a workforce in which everyone – no matter what their job title is – comes together to explore, discover and grow. And you help to foster an inclusive culture in which everyone is valued for the unique contribution they make. Current Vacancies Please note that positions for September 2024 will be open for application from August 2023. Business Operations Business Insights Analytics Health and Value Marketing Medical Affairs Regulatory Research and Development

Job Description

Site Name: 

• UK - Hertfordshire - Stevenage

• - UK – London – New Oxford Street

Posted Date: 

• Nov 11, 2024

Role Requirements:

• Must be based in a UK GSK site for a minimum of 2 days per week.

Position: 

• Clinical Development Director - Nephrology

Role Overview:

The Clinical Development Director - Nephrology will provide clinical and scientific insights to the Nephrology franchise, including emerging indications and adjacencies. The role involves working within project teams to plan and assure the delivery of clinical research and development activities. Collaboration with research members to define the best clinical indication for a target and integrating inputs from various disciplines (scientific, clinical, commercial, regulatory) is essential.

Key Responsibilities:

• Clinical Development:

•   - Design and lead clinical development protocols/studies/programs in Nephrology across all phases of development.

•   - Develop clinical development strategies, including study Ph1-2/3 design.

•   - Provide clinical expert input into regulatory documentation and lead regulatory interactions from a clinical perspective.

•   - Work with Research Unit members to define prioritized clinical indications for early targets.

•   - Integrate inputs from across disciplines to contribute to the Medicine Profile, Target Validation, Translational Plans, Candidate Selection, clinical development plan, and integrated evidence plan.

•   - Design and deliver early clinical development plans demonstrating proof of mechanism, potential efficacy, and safety profiles.

•   - Lead the integrated evidence planning to address the needs of regulators, payors, and patients.

• Regulatory and Safety:

•   - Provide clinical input into presentations and supporting documentation for governance bodies.

•   - Escalate clinical safety incidents to the Immunology Clinical Research and Early Programs Head and GSK Pharmacovigilance.

•   - Address clinical questions at meetings with regulatory authorities/ethics committees.

•   - Ensure regulatory reporting requirements, including Development Safety Update Reports (DSURs) and IB updates.

•   - Incorporate patient perspectives in the design and conduct of clinical studies.

•   - Ensure medical governance across the project to maintain scientific integrity and overall safety of study subjects.

• Leadership and Collaboration:

•   - Lead the clinical team (CT) and Integrated Evidence Team (IET).

•   - Engage external academic and clinical experts to enhance the quality and delivery of clinical programs/studies.

•   - Mentor and coach other members of Clinical Research and Early Programs Immunology.

•   - Provide input into disease area strategy and execute this strategy based on expertise.

•   - Play a leadership role in medical governance initiatives in R&D, discovery/development policy, processes, or guidelines.

•   - Network externally with academia/pharma and bring expertise back to GSK.

•   - Anticipate, communicate, and suggest solutions on trends/events outside GSK that affect business direction.

Experience and Skills:

• Experience in drug development and/or translational medicine, preferably with industry experience.

• - Ability to work across multiple projects and be independently accountable for own projects.

• - Leadership experience in medical governance initiatives and professional networks.

• - Command of the drug discovery and development process to influence a culture of continuous improvement.

This role offers an opportunity to contribute significantly to the Nephrology franchise at GSK, working with a diverse team to advance clinical research and development.

Your tasks in detail:

• Develop the regional business plan and financial objectives, supporting and reflecting central strategy.

• Lead the delivery of the business plan working in collaboration with other Takeda functions.

• Align business objectives to relevant NHS customer needs across local health economies/networks.

• Construct, present and agree with the Divisional Sales Director/Business Unit Director the financial objectives, promotional strategy and tactics for the Region as part of business planning process.

• Be accountable for the delivery of the plan across the Oncology portfolio of products, working with other field teams, their line management and Takeda Head Office functions.

• Monitor and review the regional business plan, proactively making adjustments in line with changing circumstances to ensure that business goals are achieved.

• Leverage support for products/ideas/projects across networks and to contribute to the development and mobilisation of local and national brand advocates.

• Work collaboratively with other Takeda field teams and Head Office functions to integrate working practices and differentiate Takeda effectively to leverage maximum value for the company and the NHS.

• Maintain a detailed knowledge of national policy objectives/drivers and apply this to identify opportunities for growing the business at a regional level.

• Ensure that all knowledge management and CRM systems are maintained in accordance with Takeda standards and to ensure that business plans and objectives are transparent to the Senior Leadership Team of Takeda UK.

• Possess a thorough understanding of the provisions of the APBI Code of Practice and Takeda SOPs, to ensure that the Company’s image and reputation is never jeopardised by irresponsible or unethical conduct

Job description

Site Name: USA - Pennsylvania - Upper Providence, GSK HQ, UK - Hertfordshire - Stevenage, USA - Massachusetts - Waltham

Posted Date: Feb 11 2025

Position Overview: We are seeking a dynamic and experienced Executive Director Clinical Lead for Immunology to lead our clinical development programs within the Immunology therapeutic area. This role will involve strategic oversight, leadership, and management of programmes and clinical trials, ensuring scientific integrity and adherence to regulatory requirements.

Key Responsibilities:

Provide strategic leadership and direction for the design, execution, and management to clinical development plans and clinical trials in Immunology.

Lead the end-to-end clinical development strategy for a drug or program. Manage specific clinical development plans for product(s) and/or indication(s) in specific therapy/disease areas.

Contribute to the strategic management of the Integrated Evidence Plan (IEP), including oversight of the Clinical Development Plan (CDP) and its component clinical trials for an asset in development. Be accountable for the clinical components of the Target Medicine Profile (TMP).

Oversee the development and implementation of clinical trial protocols, ensuring alignment with regulatory requirements and GSK’s scientific standards.

Collaborate with cross-functional teams, including research, regulatory affairs, medical affairs, and commercial teams, to ensure cohesive and comprehensive clinical development plans.

Serve as the primary point of contact for internal and external stakeholders, including regulatory agencies, key opinion leaders, and clinical investigators.

Ensure the integrity, safety, and efficacy of clinical trials through rigorous monitoring, data analysis, and risk management.

Lead and mentor clinical professionals, fostering a culture of innovation, collaboration, and excellence.

Manage senior clinical scientists and physician scientists (direct reports) working on Immunology assets.

Stay abreast of advancements in Rheumatology research, clinical trial methodologies, and regulatory changes to maintain GSK’s competitive edge.

Contribute to above asset Immunology strategy.

Assist in clinical evaluation of business development opportunities.

Represent GSK in scientific meetings, conferences, and industry forums to advance our Immunology clinical research initiatives.

An on-site office presence (minimum of two days a week) is required in one of GSK’s UK (London - New Oxford Street or Stevenage) or US (PA or MA) offices.